Improved research and diagnostics could help reduce the economic burden of blood disorders

Since the arrival of personalized healthcare and molecular diagnostics, there has been growing support for utilizing DNA, RNA, and protein-based biomarker detection methods as a means to help reduce rising healthcare costs (1). Molecular diagnostics can help select the right patients for the right treatments, and define which patients require costly confirmatory diagnostic tests. In… Read article →


QIAGEN’s companion diagnostic business highlighted in the Journal of Precision Medicine

A recent publication in the Journal of Precision Medicine highlights QIAGEN’s companion diagnostic business development and Modaplex platform. The July 2016 issue of the Journal_of_Precision_Medicine (JPM) features an article by Jessica Johnson called “Companion Diagnostics – a Burgeoning Market” (1). In this article, Johnson provides a brief account of the recent history of companion diagnostics… Read article →


ESMO guidelines committee update clinical recommendations for metastatic colorectal cancer

The European Society for Medical Oncology (ESMO ) is a leading European professional organization for medical oncology and is considered the reference society for oncology education and information. Comprised of more than 13,000 oncology professionals from over 130 countries, ESMO is a home for all oncology stakeholders, and connects professionals with diverse expertise and experience…. Read article →


New study suggests RT-PCR-based ALK assay useful in clinical practice

Anaplastic lymphoma kinase (ALK) gene rearrangements are found in 3–5% of lung adenocarcinomas (ADC) (2–4, Figure 1), and over 20 ALK fusion partners have been implicated in non-small-cell lung cancer (NSCLC) (5). Thanks to the relatively recent development of small molecule targeted therapies, the ALK oncogene is now targetable using ALK tyrosine kinase inhibitors (TKIs)… Read article →


QIAGEN launches novel integrated system for collection, stabilization, transport, storage and isolation of circulating cell-free DNA

Hilden, Germany, and Germantown, Maryland, July 27, 2016 – QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced the launch of the new PAXgene® Blood ccfDNA Tube* for venous whole blood collection and room temperature stabilization of in-vivo circulating cell-free DNA (ccfDNA) profiles. Together with the QIAamp Circulating Nucleic Acid Kit – the gold… Read article →


Growing evidence that MET inhibition could treat NSCLC

Evidence continues to grow for the potential therapeutic benefit of mesenchymal-epithelial transition factor proto-oncogene (MET) inhibition to treat non-small cell lung cancer (NSCLC). A recent study by Tong et al. (1) published this past June on MET DNA alterations in NSCLC provides further evidence of the critical role of aberrant MET signaling in the pathogenesis… Read article →


WHO Releases Updated Guidelines for Classification of Myeloid Neoplasms and Acute Leukemia

The right diagnosis can lead to the right treatment: Recent advances in the identification of unique biomarkers associated with some myeloid neoplasms and acute leukemia have prompted the World Health Organization (WHO) to update its 2008 Classification of Tumors of Hematopoietic Tissues (1). These revised guidelines were recently published in Blood. This new 2016 classification does… Read article →


QIAGEN partners to develop predictive tests in oncology

Yesterday, we announced that QIAGEN was entering into a licensing and co-development agreement with Therawis Diagnostics GmbH to develop and commercialize predictive assays in oncology. An initial project will be to develop and market PITX2 as a marker to predict effectiveness of anthracycline treatment in triple negative and other high-risk breast cancer patients. See the full press release… Read article →


Infographic: Filtering the flood

The global DNA sequencing capacity is increasing 3x-5x per year, leading to an unprecedented flood of biological data. Already, the output of biological data amounts to 15 petabytes a year (the equivalent of >3 million DVDs) and its amount doubles every 9 months, making it hard for scientists to keep up and put the information… Read article →